Researchers at the Max Planck Institute for Metabolism Research have discovered that the brain plays a crucial role in initiating autophagy, the body’s waste disposal system, during fasting. Contrary to previous assumptions that liver cells themselves activate autophagy, the study found that the brain triggers the release of the hormone corticosterone, which stimulates autophagy in…
Author: OptimalJourney
Cold exposure inhibits Cancer
New research suggests that continuous exposure to cold temperatures can impede the growth of cancerous cells by activating brown fat cells and depleting their main energy source, glucose. A study conducted on mice and one person with Hodgkin’s lymphoma demonstrated that cold therapy significantly inhibited tumour growth and improved survival rates. By altering the body’s…
Intermittent Fasting Step-by-Step
Transitioning into Intermittent Fasting: Guide to Success Intermittent fasting, has gained popularity as an effective approach for weight loss through caloric restriction, improved metabolic health, and increased mental clarity. Transitioning into intermittent fasting gradually can help your body adapt to the fasting periods more comfortably. In this article, we will outline a step-by-step guide to…
Supplements for Extended Fasts
During an extended fast, it’s crucial to prioritize hydration and maintain electrolyte balance, especially if you are active during your fast. As your body enters a state of ketosis, it utilizes stored fat as its primary source of energy. Similar to a hybrid car, your body can switch between using glucose and fat as fuels….
Rodent-Human Timescale Variations
In the realm of scientific research, mice have long served as a valuable model organism for studying various biological processes, including fasting. Many groundbreaking studies on fasting and its potential health benefits have been conducted on mice, yielding valuable insights and paving the way for further investigation. However, it is essential to acknowledge and address…
From Hunter-Gatherers to Modern Fasting
Throughout the course of human history, the existence of modern humans on Earth spans approximately 200,000 years. It is an awe-inspiring timeline that reveals our ancient roots and the vast expanse of time during which our species has evolved. For the majority of this immense duration, humans were primarily hunter-gatherers, relying on their skills to…
Autophagy: Advances and Legacy
In 2021, the scientific community celebrated the achievements of two prominent Hungarian scientists, Professor János Kovács and Professor Miklós Sass, for their contributions to the field of autophagy. These scientists were among the early pioneers in studying autophagy, specifically during insect metamorphosis. They established an autophagy research center at Eötvös Loránd University in Budapest, where…